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Preparation of two-photon fluorescent probe and biological imaging application in cells
Chi SH(迟书恒); Li L(李亮); Wu YQ(吴谊群); yqwu@siom.ac.cn
2016
Source PublicationChin. Opt. Lett.
Volume14Issue:6
AbstractWe report on a novel dibenzothiophene-based two-photon fluorescent probe for selective nuclear bioimaging, which contains bilaterally symmetrical pyridine rings connected by a central conjugated-bridge dibenzothiophene. This probe possesses a large two-photon absorption cross-section of 471 GM, yields a 25-fold enhancement of the fluorescence titration, and a stronger photostability for nuclei labeling than existing probes. The real-time observation period is a minimum of 1800 s under a femtosecond laser excitation, which is significantly longer than that of 4',6-diamidino-2-phenylindole. The above results confirm that this novel molecule is a suitable two-photon fluorescent probe for application to nuclear bioimaging in cells.
SubtypeArticle
Department存储
DOI10.3788/COL201614.061603
Funding OrganizationNational Natural Science Foundation of China [61137002, 61178059, 51172253] ; National Natural Science Foundation of China [61137002, 61178059, 51172253] ; National Natural Science Foundation of China [61137002, 61178059, 51172253] ; National Natural Science Foundation of China [61137002, 61178059, 51172253]
Indexed BySCI
Funding OrganizationNational Natural Science Foundation of China [61137002, 61178059, 51172253] ; National Natural Science Foundation of China [61137002, 61178059, 51172253] ; National Natural Science Foundation of China [61137002, 61178059, 51172253] ; National Natural Science Foundation of China [61137002, 61178059, 51172253]
WOS IDWOS:000378344500016
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Document Type期刊论文
Identifierhttp://ir.siom.ac.cn/handle/181231/28252
Collection高密度光存储技术实验室
Corresponding Authoryqwu@siom.ac.cn
Affiliation中国科学院上海光学精密机械研究所
Recommended Citation
GB/T 7714
Chi SH,Li L,Wu YQ,et al. Preparation of two-photon fluorescent probe and biological imaging application in cells[J]. Chin. Opt. Lett.,2016,14(6).
APA 迟书恒,李亮,吴谊群,&yqwu@siom.ac.cn.(2016).Preparation of two-photon fluorescent probe and biological imaging application in cells.Chin. Opt. Lett.,14(6).
MLA 迟书恒,et al."Preparation of two-photon fluorescent probe and biological imaging application in cells".Chin. Opt. Lett. 14.6(2016).
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