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Ptychographic phase microscope based on high-speed modulation on the illumination beam
Yao, Yudong; Veetil, Suhas P.; Liu, Cheng; Zhu, JianQiang; cheng.liu@hotmail.co.uk
2017
Source PublicationJ. Biomed. Opt.
Volume22Issue:3
AbstractA type of ptychography-based phase microscope was developed by integrating a spatial light modulator (SLM) into a commercial wide-field light microscope. By displaying a moving pattern on the SLM to change the sample illumination and record the diffraction intensities formed, both the modulus and phase of the transmission function of the sample could be accurately reconstructed with formulas similar to those of common ptychography. Compared with other kinds of phase microscopes, the developed microscope has several advantages, including its simple structure, high immunity to coherent noise, and low requirement for quality optics. In addition, defects in the illumination beam are also removed from the reconstructed image. Further, this microscope's fast data acquisition ability makes it highly suitable for many applications where highly accurate quantitative phase imaging is important, such as in living cells or other fragile biological samples that cannot sustain continuous imaging over a long period of time. (C) 2017 Society of Photo-Optical Instrumentation Engineers (SPIE)
SubtypeArticle
Department联合
DOI10.1117/1.JBO.22.3.036010
Funding OrganizationChinese Academy of Sciences (CAS) [902012312D1100101]; CAS [29201431151100301] ; Chinese Academy of Sciences (CAS) [902012312D1100101]; CAS [29201431151100301] ; Chinese Academy of Sciences (CAS) [902012312D1100101]; CAS [29201431151100301] ; Chinese Academy of Sciences (CAS) [902012312D1100101]; CAS [29201431151100301]
Indexed BySCI
Funding OrganizationChinese Academy of Sciences (CAS) [902012312D1100101]; CAS [29201431151100301] ; Chinese Academy of Sciences (CAS) [902012312D1100101]; CAS [29201431151100301] ; Chinese Academy of Sciences (CAS) [902012312D1100101]; CAS [29201431151100301] ; Chinese Academy of Sciences (CAS) [902012312D1100101]; CAS [29201431151100301]
WOS IDWOS:000397944900025
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Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.siom.ac.cn/handle/181231/27896
Collection高功率激光物理国家实验室
Corresponding Authorcheng.liu@hotmail.co.uk
Affiliation中国科学院上海光学精密机械研究所
Recommended Citation
GB/T 7714
Yao, Yudong,Veetil, Suhas P.,Liu, Cheng,et al. Ptychographic phase microscope based on high-speed modulation on the illumination beam[J]. J. Biomed. Opt.,2017,22(3).
APA Yao, Yudong,Veetil, Suhas P.,Liu, Cheng,Zhu, JianQiang,&cheng.liu@hotmail.co.uk.(2017).Ptychographic phase microscope based on high-speed modulation on the illumination beam.J. Biomed. Opt.,22(3).
MLA Yao, Yudong,et al."Ptychographic phase microscope based on high-speed modulation on the illumination beam".J. Biomed. Opt. 22.3(2017).
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